Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.57 |
| ▸ | CNR1 | P21554 | 8/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946747 | 0.91 | CNR2 (0.67) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL3034727 | 0.84 | CNR2 (0.57) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL3948637 | 0.84 | CNR2 (0.60) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL28245769 | 0.83 | THRA (0.61) | TSHRMEN1KMT2ACYSLTR2CYSLTR1 | |
| SCHEMBL4113024 | 0.82 | CNR2 (0.72) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL3030328 | 0.82 | CNR2 (0.55) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL4115449 | 0.82 | CNR2 (0.72) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL4108174 | 0.82 | CNR2 (0.72) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL3948574 | 0.82 | TSHR (0.55) | CNR2CNR1TSHRMEN1KMT2A | |
| SCHEMBL28245759 | 0.82 | THRA (0.60) | TSHRMEN1KMT2ACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | claimed |
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021590-A1 | TYROSINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |