Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605490 | 0.78 | SIGMAR1 (0.64) | CARM1PRMT6KMT2ASIGMAR1 | |
| SCHEMBL2307774 | 0.76 | SIGMAR1 (0.60) | KMT2AHTR1ASIGMAR1S1PR1GRK5 | |
| SCHEMBL4702695 | 0.76 | KMT2A (0.53) | CARM1PRMT6KMT2AHTR1AMAOB | |
| SCHEMBL28664674 | 0.75 | SIGMAR1 (0.44) | CHRM3SIGMAR1 | |
| SCHEMBL5709472 | 0.75 | HTR2A (0.50) | CARM1PRMT6CHRM3SIGMAR1 | |
| SCHEMBL11747882 | 0.74 | SIGMAR1 (0.56) | HTR1AMAOBSIGMAR1 | |
| SCHEMBL29042304 | 0.74 | MAOB (0.51) | CARM1PRMT6EPHX1MAOBSIGMAR1 | |
| SCHEMBL10899474 | 0.74 | SIGMAR1 (0.60) | KMT2AHTR1ASIGMAR1S1PR1GRK5 | |
| SCHEMBL5695484 | 0.73 | SIGMAR1 (0.63) | HTR1AMAOBSIGMAR1 | |
| SCHEMBL22499786 | 0.73 | NOTUM (0.62) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
| CN-1921858-A | Piperidinylalkylcarbamate derivatives, process for their preparation and their use as FAAH enzyme inhibitors | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | CN | disclosed |
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |