Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26814047 | 0.76 | KCNA3 (0.51) | SIGMAR1 | |
| SCHEMBL28681273 | 0.76 | CHRM3 (0.52) | CHRM3 | |
| SCHEMBL3947610 | 0.75 | CARM1 (0.52) | SIGMAR1CHRM3 | |
| SCHEMBL28662442 | 0.73 | CHRM3 (0.44) | CHRM3 | |
| SCHEMBL5709503 | 0.73 | DRD2 (0.61) | SIGMAR1CHRM3 | |
| SCHEMBL28662777 | 0.72 | TEAD3 (0.59) | KDM4E | |
| SCHEMBL10442916 | 0.72 | GNAI3 (0.54) | CHRM3 | |
| Biphenyl SCHEMBL1191470 | 0.71 | CHRM3 (0.52) | CHRM3 | |
| SCHEMBL186785 | 0.71 | BCHE (0.67) | SIGMAR1 | |
| SCHEMBL17967824 | 0.70 | ALDH1A1 (0.53) | KDM4ECHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784969-A | PLK1 Selective degradation inducing Compounds | 厄普特拉公司 | 2021-12-10 | — | — | CN | disclosed |