Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990682 | 0.80 | SMN1; SMN2 (0.53) | CTSDNPC1SMN1; SMN2MAOBLMNA | |
| SCHEMBL5446678 | 0.79 | ERCC5 (0.41) | SMN1; SMN2HPGDLMNAGAAHTT | |
| SCHEMBL28518383 | 0.77 | NPC1 (0.50) | CTSDNPC1SMN1; SMN2MAOBHPGD | |
| SCHEMBL4598908 | 0.77 | CES2 (0.48) | NPC1HPGDLMNARAB9AGAA | |
| SCHEMBL9141895 | 0.76 | NPC1 (0.62) | CTSDNPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL9559943 | 0.75 | CTSD (0.56) | CTSDNPC1SMN1; SMN2MAOBLMNA | |
| SCHEMBL855233 | 0.74 | MAPT (0.57) | CTSDNPC1SMN1; SMN2HPGDSTAT3 | |
| SCHEMBL710253 | 0.73 | NR4A1 (0.49) | HPGDLMNATP53GAAHTT | |
| SCHEMBL9072150 | 0.73 | NPC1 (0.62) | CTSDNPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL27758670 | 0.73 | CTSD (0.53) | CTSDNPC1SMN1; SMN2HPGDSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745143-A4 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | CAMBREX BIO SCIENCE WALKERSVIL (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2009026338-A1 | INTRACELLULAR REPORTERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-1745143-A1 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | Cambrex Bio Science Walkersville, Inc (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005113794-A1 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | CAMBREX BIO SCIENCE WALKERSVILLE, INC. (US) | 2005-12-01 | — | — | WO | disclosed |