Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952872 | 0.86 | PIM1 (0.30) | PIM1 | |
| SCHEMBL3948245 | 0.84 | GNAI3 (0.33) | NAMPTPIM1 | |
| SCHEMBL3951429 | 0.84 | DRD2 (0.31) | PIM1 | |
| SCHEMBL3954973 | 0.79 | ALDH1A1 (0.38) | — | |
| SCHEMBL3955855 | 0.79 | PIM1 (0.30) | PIM1 | |
| SCHEMBL3951433 | 0.79 | CARM1 (0.43) | — | |
| SCHEMBL3946753 | 0.79 | PIM1 (0.32) | PIM1 | |
| SCHEMBL3957664 | 0.79 | RAD52 (0.38) | PIM1 | |
| SCHEMBL3954983 | 0.76 | KEAP1 (0.32) | — | |
| SCHEMBL3947080 | 0.76 | KEAP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |