Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.46 |
| ▸ | CPT2 | P23786 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951883 | 0.84 | L3MBTL1 (0.44) | CPT1ACPT1BCPT2DRD2ADRA1D | |
| SCHEMBL3949063 | 0.80 | L3MBTL1 (0.47) | CPT1ACPT1BCPT2DRD2ADRA1D | |
| SCHEMBL3950301 | 0.78 | CPT2 (0.41) | CPT1ACPT1BCPT2DRD2ADRA1D | |
| SCHEMBL13662066 | 0.78 | CPT1A (0.54) | CPT1ACPT1BCPT2DRD2ADRA1D | |
| SCHEMBL4294665 | 0.77 | CPT2 (0.53) | CPT1ACPT1BCPT2DRD2ADRA1D | |
| SCHEMBL3947805 | 0.76 | CTSL (0.47) | KMT2AL3MBTL1SMN1; SMN2TP53CASP1 | |
| SCHEMBL8045577 | 0.75 | CPT2 (0.50) | CPT1ACPT1BCPT2DRD2ADRA1D | |
| SCHEMBL3952237 | 0.74 | L3MBTL1 (0.45) | DRD2ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL3954902 | 0.73 | KMT2A (0.47) | DRD2ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL3950238 | 0.73 | MAPK1 (0.37) | KMT2AGAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |