Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.53 |
| ▸ | CPT1A | P50416 | 1/20 | 0.53 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301195 | 0.92 | CTSL (0.51) | CPT2CPT1ACPT1BKMT2ADRD2 | |
| SCHEMBL8045577 | 0.91 | CPT2 (0.50) | CPT2CPT1ACPT1BGAAKMT2A | |
| SCHEMBL13662066 | 0.91 | CPT1A (0.54) | CPT2CPT1ACPT1BGAAKMT2A | |
| SCHEMBL4294636 | 0.83 | CPT2 (0.51) | CPT2CPT1ACPT1BKMT2ADRD2 | |
| SCHEMBL8064342 | 0.83 | CTSL (0.47) | CPT2CPT1ACPT1BKMT2ADRD2 | |
| SCHEMBL13662067 | 0.82 | CTSL (0.52) | CPT2CPT1ACPT1BKMT2ADRD2 | |
| SCHEMBL4298295 | 0.81 | CPT2 (0.50) | CPT2CPT1ACPT1BGAAKMT2A | |
| SCHEMBL4294690 | 0.79 | CTSL (0.46) | KMT2ACTSLCTSSCTSKCTSC | |
| SCHEMBL4290366 | 0.79 | CPT2 (0.48) | CPT2CPT1ACPT1BKMT2ADRD2 | |
| SCHEMBL4298985 | 0.79 | CTSL (0.55) | CPT2CPT1ACPT1BDRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264431-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264431-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | CTSB, CTSS, CTSF | CPT2 3009/4885CPT1A 3354/4885CPT1B 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.