SCHEMBL6526046

SCHEMBL6526046

O=C1OC(c2ccccc2O)(c2ccccc2O)c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 1/20 0.64
GNB1 P62873 1/20 0.64
MAPT P10636 5/20 0.64
LMNA P02545 5/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
TDP1 Q9NUW8 4/20 0.64
GPR55 Q9Y2T6 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
TP53 P04637 2/20 0.64
CYP3A4 P08684 2/20 0.64
ALOX15 P16050 2/20 0.64
ALDH1A1 P00352 1/20 0.64
ESR1 P03372 1/20 0.64
TYMS P04818 1/20 0.64
TSHR P16473 1/20 0.64
ESR2 Q92731 1/20 0.64
HSD17B10 Q99714 1/20 0.64
CFTR P13569 1/20 0.61
GOPC Q9HD26 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14580568 0.87 MAPT (0.82) GNG2GNB1MAPTLMNAMEN1
SCHEMBL3949342 0.86 CFTR (0.73) GNG2GNB1MAPTLMNAMEN1
SCHEMBL30772290 0.86 CFTR (0.73) GNG2GNB1MAPTLMNAMEN1
SCHEMBL14749014 0.84 GNG2 (0.56) GNG2GNB1MAPTLMNAMEN1
SCHEMBL16285463 0.84 MAPT (0.73) GNG2GNB1MAPTLMNAMEN1
SCHEMBL3653457 0.84 GNG2 (0.77) GNG2GNB1MAPTLMNAMEN1
SCHEMBL4961617 0.82 GNG2 (0.54) GNG2GNB1MAPTLMNAMEN1
SCHEMBL11303073 0.82 LMNA (0.65) GNG2GNB1MAPTLMNAMEN1
SCHEMBL63922 0.81 GNG2 (0.64) GNG2GNB1MAPTLMNAMEN1
SCHEMBL16283358 0.81 MAPT (0.56) GNG2GNB1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0073758-A4 TREATMENT OF INFLAMMATORY VIRAL INFECTIONS, ACNE, DERMATITIS AND ARTHRITIS CONDITIONS. MCHUGH JOHN EDWARD 1983-07-04 EP claimed
EP-0073758-A1 TREATMENT OF INFLAMMATORY VIRAL INFECTIONS, ACNE, DERMATITIS AND ARTHRITIS CONDITIONS. MCHUGH JOHN EDWARD 1983-03-16 EP claimed
WO-1982003010-A1 TREATMENT OF INFLAMMATORY VIRAL INFECTIONS,ACNE,DERMATITIS AND ARTHRITIS CONDITIONS MCHUGH JOHN EDWARD 1982-09-16 WO claimed
EP-1498441-A1 Temperature curable compositions with low temperature impact strength modifier Sika Technology AG (CH) 2005-01-19 EP disclosed
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed