Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 6/20 | 0.53 |
| ▸ | PMM2 | O15305 | 5/20 | 0.53 |
| ▸ | MIF | P14174 | 6/20 | 0.53 |
| ▸ | G6PD | P11413 | 3/20 | 0.50 |
| ▸ | PHOSPHO1 | Q8TCT1 | 6/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | MMP10 | P09238 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953369 | 0.90 | G6PD (0.55) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL8370750 | 0.84 | MPI (0.52) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL8371737 | 0.82 | MIF (0.59) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL8372534 | 0.77 | MPI (0.72) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL8373532 | 0.74 | MIF (0.74) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL8373420 | 0.72 | G6PD (0.80) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL8371833 | 0.71 | PHOSPHO1 (0.50) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL2538424 | 0.70 | MPI (1.00) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL22092579 | 0.69 | MIF (1.00) | MPIPMM2MIFG6PDPHOSPHO1 | |
| SCHEMBL3947528 | 0.69 | G6PD (0.50) | MPIPMM2MIFG6PDPHOSPHO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | claimed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | claimed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | claimed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | claimed |
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | disclosed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142587-A1 | Benzoisothiazolone compositions | COL1A1, TYR, CUTA | MPI 3471/4885PMM2 4486/4885MIF 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.