Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291538 | 0.84 | TDP1 (0.56) | CES1CES2TSHRALDH1A1DAO | |
| Benzoyl Formic Acid SCHEMBL31113414 | 0.79 | CES2 (0.72) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL10375317 | 0.79 | CES2 (0.72) | CES1CES2TSHRALDH1A1DAO | |
| Benzophenone SCHEMBL4382632 | 0.78 | ALDH1A1 (0.93) | CES1CES2TSHRALDH1A1DAO | |
| Benzoic Acid SCHEMBL1052340 | 0.78 | TSHR (0.93) | CES1CES2TSHRALDH1A1DAO | |
| Benzoic Acid SCHEMBL29215589 | 0.78 | TSHR (0.93) | CES1CES2TSHRALDH1A1DAO | |
| Benzil SCHEMBL5962228 | 0.78 | CES2 (0.93) | CES1CES2TSHRALDH1A1DAO | |
| Benzoic Acid SCHEMBL29076240 | 0.78 | TSHR (0.93) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL2905276 | 0.77 | TDP1 (0.62) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1683825 | 0.77 | CES1 (0.64) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090026415-A1 | Process to Produce an Enriched Composition | EASTMAN CHEMICAL COMPANY (US) | 2009-01-29 | — | — | US | claimed |
| EP-3134402-B1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2020-05-06 | — | — | EP | disclosed |
| EP-2066612-B1 | A PROCESS TO PRODUCE AN ENRICHMENT FEED | GRUPO PETROTEMEX SA DE CV (MX) | 2018-08-01 | — | — | EP | disclosed |
| EP-3134402-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2017-03-01 | — | — | EP | disclosed |
| US-9447097-B2 | 4-amino-imidazoquinoline compounds | HOFFMANN-LA ROCHE INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160222010-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-9334268-B2 | 4-amino-imidazoquinoline compounds | HOFFMAN-LA ROCHE INC. (US) | 2016-05-10 | — | — | US | disclosed |
| WO-2015162075-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-10-29 | — | — | WO | disclosed |
| US-20150299194-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2015-10-22 | — | — | US | disclosed |
| EP-1890809-A4 | HYDROTREATING POLYESTER PRECURSORS | EASTMAN CHEM CO (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1890809-A2 | HYDROTREATING POLYESTER PRECURSORS | EASTMAN CHEMICAL COMPANY (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006138030-A2 | HYDROTREATING POLYESTER PRECURSORS | EASTMAN CHEMICAL COMPANY (US) | 2006-12-28 | — | — | WO | disclosed |
| US-7067615-B1 | Hydrotreating polyester precursors | EASTMAN CHEMICAL COMPANY (US) | 2006-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222010-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | TLR4, TLR1, TLR5 | CES1 3953/4885CES2 3611/4885TSHR 1049/4885 |
| US-20150299194-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS | TLR4, TLR1, TLR5 | CES1 3953/4885CES2 3611/4885TSHR 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.