SCHEMBL12641

SCHEMBL12641

CCCC1CCN(C(C)=O)CC1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.45
GNAO1 P09471 2/20 0.45
GNAI1 P63096 2/20 0.45
EPHX2 P34913 5/20 0.42
EPHX1 P07099 2/20 0.42
CYP1A2 P05177 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
REV1 Q9UBZ9 1/20 0.41
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13560161 0.93 EPHX2 (0.41) GNAI3GNAO1GNAI1EPHX2EPHX1
SCHEMBL13509613 0.88 GNAI3 (0.40) GNAI3GNAO1GNAI1EPHX2EPHX1
SCHEMBL12561511 0.88 POLB (0.51) GNAI3GNAO1GNAI1EPHX2EPHX1
SCHEMBL18897210 0.88 GNAI3 (0.40) GNAI3GNAO1GNAI1EPHX2EPHX1
SCHEMBL13597080 0.86 GNAI3 (0.53) GNAI3GNAO1GNAI1CYP1A2POLB
SCHEMBL22562145 0.85 GNAI3 (0.55) GNAI3GNAO1GNAI1POLBHPGD
SCHEMBL18761634 0.85 GNAI3 (0.55) GNAI3GNAO1GNAI1POLBHPGD
SCHEMBL1501881 0.83 AKR1C3 (0.43) GNAI3GNAO1GNAI1EPHX2EPHX1
SCHEMBL3955878 0.83 EPHX2 (0.42) GNAI3GNAO1GNAI1EPHX2EPHX1
SCHEMBL12016032 0.83 GNAI3 (0.45) GNAI3GNAO1GNAI1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393922-A1 IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) 2024-07-03 EP disclosed
US-20230357177-A1 SYNTHESIS OF CANNABIDIOL AND ANALOGS THEREOF, AND RELATED COMPOUNDS, FORMULATIONS, AND METHODS OF USE NALU BIO, INC. 2023-11-09 US disclosed
US-20230357177-A1 SYNTHESIS OF CANNABIDIOL AND ANALOGS THEREOF, AND RELATED COMPOUNDS, FORMULATIONS, AND METHODS OF USE NALU BIO, INC. 2023-11-09 US disclosed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
EP-4194457-A1 COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) 2023-06-14 EP disclosed
WO-2023060369-A1 NOVEL CARBIMIDATE SUBSTITUTED BICYCLIC COMPOUNDS AND THEIR USE AS BETA-LACTAMASE INHIBITORS NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) 2023-04-20 WO disclosed
WO-2023049808-A2 SMALL MOLECULE INHIBITORS OF TEAD-YAP THE GENERAL HOSPITAL CORPORATION (US) 2023-03-30 WO disclosed
US-20220153732-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2022-05-19 US disclosed
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2021-01-05 US disclosed
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-02-25 US disclosed
US-7491748-B2 Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2009-02-17 US disclosed
US-20080227834-A1 DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS SANOFI-AVENTIS (FR) 2008-09-18 US disclosed
US-20080227834-A1 DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS SANOFI-AVENTIS (FR) 2008-09-18 US disclosed
US-20080182783-A1 Growth Hormone Conjugates NOVO NORDISK A/S (DK) 2008-07-31 US disclosed
WO-2006042848-A9 GROWTH HORMONE CONJUGATES NOVO NORDISK AS (DK) 2007-05-18 WO disclosed
US-20070111926-A1 Conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-17 US disclosed
US-20070111926-A1 Conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-17 US disclosed
US-20070105770-A1 Transglutaminase mediated conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-10 US disclosed
US-20070105770-A1 Transglutaminase mediated conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-10 US disclosed
WO-2007039176-A1 DERIVATIVES OF 2 -AMINTHIAZOLES AND 2-AMINOOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI-AVENTIS (DE) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227834-A1 DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS PPARA, PPARD, PPARG GNAI3 3289/4885GNAO1 2488/4885GNAI1 3094/4885
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors SERPINB1, FURIN, HIF1AN GNAI3 952/4885GNAO1 3623/4885GNAI1 784/4885
US-20230357177-A1 SYNTHESIS OF CANNABIDIOL AND ANALOGS THEREOF, AND RELATED COMPOUNDS, FORMULATIONS, AND METHODS OF USE HMBS, CNR2, HPD GNAI3 1472/4885GNAO1 699/4885GNAI1 1585/4885
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 GNAI3 960/4885GNAO1 2127/4885GNAI1 679/4885
US-20070105770-A1 Transglutaminase mediated conjugation of peptides TGM2, TGM3, TGM1 GNAI3 1834/4885GNAO1 3325/4885GNAI1 1692/4885
US-20220153732-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G GNAI3 325/4885GNAO1 1799/4885GNAI1 247/4885
US-20080182783-A1 Growth Hormone Conjugates GHRHR, GHSR, GHITM GNAI3 2317/4885GNAO1 864/4885GNAI1 2319/4885
US-20070111926-A1 Conjugation of peptides DNPEP, ENPEP, ANPEP GNAI3 4253/4885GNAO1 4716/4885GNAI1 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.