Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 13/20 | 0.34 |
| ▸ | HTR2A | P28223 | 13/20 | 0.34 |
| ▸ | DRD3 | P35462 | 13/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949391 | 0.94 | ALDH1A1 (0.41) | ALDH1A1DRD2DRD3SIGMAR1LMNA | |
| SCHEMBL3950698 | 0.93 | ALDH1A1 (0.34) | ALDH1A1DRD2HTR2ADRD3SIGMAR1 | |
| SCHEMBL3950772 | 0.88 | ALDH1A1 (0.36) | ALDH1A1DRD2DRD3SIGMAR1LMNA | |
| SCHEMBL3956154 | 0.81 | CYP1A2 (0.35) | ALDH1A1DRD2HTR2ADRD3 | |
| SCHEMBL3949734 | 0.81 | SIGMAR1 (0.37) | ALDH1A1DRD2DRD3SIGMAR1LMNA | |
| SCHEMBL3955895 | 0.81 | GNAO1 (0.40) | DRD2DRD3SIGMAR1 | |
| SCHEMBL3950841 | 0.80 | ALDH1A1 (0.39) | ALDH1A1DRD2HTR2ADRD3 | |
| SCHEMBL3950649 | 0.79 | CHRM1 (0.40) | ALDH1A1DRD2DRD3SIGMAR1 | |
| SCHEMBL3947898 | 0.78 | HTR2A (0.38) | ALDH1A1DRD2HTR2ADRD3 | |
| SCHEMBL4045145 | 0.77 | HRH3 (0.39) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |