Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 4/20 | 0.62 |
| ▸ | CES1 | P23141 | 4/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARD | Q03181 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | FABP4 | P15090 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279838 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL9730057 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL300211 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL10807672 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL20067018 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL14917692 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL11246992 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL2528166 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL5873457 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL28477653 | 1.00 | KMT2A (0.65) | KMT2AMAPTCES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240224999-A1 | METABOLIC INHIBITORS FOR CONTROLLING BIOFILM | MC US 3 LLC (US) | 2024-07-11 | — | — | US | disclosed |
| US-20230183640-A1 | METABOLIC INHIBITORS WITH EFFICACY FOR INHIBITING SULFIDE PRODUCTION IN HARSH ENVIRONMENTS | LANXESS CORPORATION | 2023-06-15 | — | — | US | disclosed |
| EP-2051955-B1 | PRODUCTION OF ALPHA HYDROXY KETONES VIA CARBENE CATALYZED POLE REVERSAL REACTION OF ALDEHYDES | EVONIK DEGUSSA GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| EP-2051955-B1 | PRODUCTION OF ALPHA HYDROXY KETONES VIA CARBENE CATALYZED POLE REVERSAL REACTION OF ALDEHYDES | EVONIK DEGUSSA GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| WO-2013157651-A1 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-24 | — | — | WO | disclosed |
| US-20120000533-A1 | PHOTOELECTRIC CONVERSION DEVICE COMPRISING HYDROXAMIC ACID OR A SALT THEREOF AS ADDITIVE AND PROCESS FOR PRODUCING SAME | BASF SE (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20090306163-A1 | TOPICAL COMPOSITIONS COMPRISING IMIDAZOLIDINEDIONE ANALOGS AND THEIR USE TO TREAT OR PREVENT THE APPEARANCE OF SKIN WRINKLING | LIPKIN PAMELA RENEE | 2009-12-10 | — | — | US | disclosed |
| EP-2051955-A1 | PRODUCTION OF ALPHA HYDROXY KETONES VIA CARBENE CATALYZED POLE REVERSAL REACTION OF ALDEHYDES | Evonik Degussa GmbH (DE) | 2009-04-29 | — | — | EP | disclosed |
| US-7504542-B2 | Preparation of α-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | EVONIK DEGUSSA GMBH (DE) | 2009-03-17 | — | — | US | disclosed |
| US-7504542-B2 | Preparation of α-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | EVONIK DEGUSSA GMBH (DE) | 2009-03-17 | — | — | US | disclosed |
| US-7504542-B2 | Preparation of α-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | EVONIK DEGUSSA GMBH (DE) | 2009-03-17 | — | — | US | disclosed |
| US-20080051608-A1 | Preparation of alpha-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | DEGUSSA GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051608-A1 | Preparation of alpha-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | DEGUSSA GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051608-A1 | Preparation of alpha-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | DEGUSSA GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| WO-2008019927-A1 | PRODUCTION OF ALPHA HYDROXY KETONES VIA CARBENE CATALYZED POLE REVERSAL REACTION OF ALDEHYDES | EVONIK DEGUSSA GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008019927-A1 | PRODUCTION OF ALPHA HYDROXY KETONES VIA CARBENE CATALYZED POLE REVERSAL REACTION OF ALDEHYDES | EVONIK DEGUSSA GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |
| US-6861402-B1 | Pro-fragrances | THE PROCTER & GAMBLE COMPANY (US) | 2005-03-01 | — | — | US | disclosed |
| EP-0108627-A2 | Cephalosporin derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051608-A1 | Preparation of alpha-hydroxy ketones via carbene-catalyzed umpolung reaction of aldehydes | HACL2, PCCA, ECI1 | KMT2A 3477/4885MAPT 4034/4885CES2 915/4885 |
| US-20090306163-A1 | TOPICAL COMPOSITIONS COMPRISING IMIDAZOLIDINEDIONE ANALOGS AND THEIR USE TO TREAT OR PREVENT THE APPEARANCE OF SKIN WRINKLING | CUTA, COL14A1, PDE7B | KMT2A 3662/4885MAPT 2404/4885CES2 3402/4885 |
| US-20240224999-A1 | METABOLIC INHIBITORS FOR CONTROLLING BIOFILM | RIMKLA, HDHD5, SCD | KMT2A 1215/4885MAPT 3340/4885CES2 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.