Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777983 | 0.88 | LMNA (0.65) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL3952100 | 0.86 | L3MBTL1 (0.63) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829589 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL24627828 | 0.84 | L3MBTL1 (0.62) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829559 | 0.84 | LMNA (0.63) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829554 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL3811564 | 0.82 | L3MBTL1 (0.80) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL24627820 | 0.82 | L3MBTL1 (0.58) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL28693300 | 0.81 | LMNA (0.63) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL7372302 | 0.81 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2L3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027679-A1 | PROCESS FOR THE PREPARATION OF GUANIDINO SUBSTITUTED BI-AND POLYPHENYLS THAT ARE SUITABLE AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2009-03-05 | — | — | WO | disclosed |