Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829577 | 0.96 | HTT (0.58) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829559 | 0.88 | LMNA (0.63) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829556 | 0.85 | HTT (0.59) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829589 | 0.84 | LMNA (0.65) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL3952102 | 0.83 | LMNA (0.67) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL29777983 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL30829573 | 0.80 | TGM2 (0.57) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL6630507 | 0.80 | LMNA (0.56) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL3811564 | 0.79 | L3MBTL1 (0.80) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL24627828 | 0.79 | L3MBTL1 (0.62) | LMNASMN1; SMN2L3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590673-A1 | FLUORESCENT PROBES FOR MAGL | F. Hoffmann-La Roche AG (CH) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024061853-A1 | FLUORESCENT PROBES FOR MAGL | F. HOFFMANN-LA ROCHE AG (CH) | 2024-03-28 | — | — | WO | disclosed |