Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228533 | 0.76 | MAP2 (0.43) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL5736875 | 0.74 | MAPT (0.41) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL6859385 | 0.73 | HTR6 (0.61) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL3957063 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL5737134 | 0.71 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL31416345 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL9023820 | 0.70 | MAPT (0.46) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL3957070 | 0.69 | TUBB4A (0.59) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL4236195 | 0.68 | KDM4E (0.38) | ALDH1A1HPGDKDM4EMAPTPTPN5 | |
| SCHEMBL31416387 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078029-A2 | ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008042240-A9 | ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS | IDENIX PHARMACEUTICALS INC (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008042240-A2 | ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2008-04-10 | — | — | WO | disclosed |