Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738353 | 0.89 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5738604 | 0.85 | MAOB (0.40) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5739744 | 0.82 | SCD (0.42) | KDM4EMEN1KMT2APOLBSCD | |
| SCHEMBL7003912 | 0.80 | LTB4R2 (0.43) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL5738764 | 0.75 | MAOB (0.42) | MAPTNPC1MEN1KMT2APOLB | |
| SCHEMBL3954170 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL2810771 | 0.73 | HTR6 (0.56) | MAPTALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL5767326 | 0.72 | CCR1 (0.39) | HPGDMEN1KMT2AGAALMNA | |
| SCHEMBL5270452 | 0.70 | MAPT (0.38) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5737493 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |