SCHEMBL3954299

SCHEMBL3954299

C=COCOc1ccccc1OCOC=C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
LMNA P02545 3/20 0.37
MAPT P10636 3/20 0.37
JAK2 O60674 1/20 0.37
GAA P10253 1/20 0.37
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LIG1 P18858 1/20 0.33
ADRB2 P07550 2/20 0.33
ADRB1 P08588 2/20 0.33
SLC22A1 O15245 1/20 0.33
CYP1A2 P05177 1/20 0.33
HTR1A P08908 1/20 0.33
CYP2D6 P10635 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17667230 0.82 ADRB2 (0.53) KDM4ELMNAGAAALDH1A1SMN1; SMN2
SCHEMBL1506175 0.79 MAPT (0.50) KDM4ELMNAMAPTJAK2GAA
SCHEMBL5707376 0.79 KCNA3 (0.46) KDM4ELMNAGAAALDH1A1SMN1; SMN2
SCHEMBL15611249 0.78 SLC6A2 (0.35) LMNAALDH1A1SMN1; SMN2SLC6A4
SCHEMBL7180242 0.75 NQO1 (0.38) ALDH1A1SMN1; SMN2TSHRL3MBTL1
SCHEMBL30741241 0.72 CA12 (0.48) KDM4ELMNAMAPTJAK2GAA
SCHEMBL3185351 0.72 CA12 (0.48) KDM4ELMNAMAPTJAK2GAA
SCHEMBL30741239 0.72 CA12 (0.48) KDM4ELMNAMAPTJAK2GAA
SCHEMBL11411513 0.71 L3MBTL1 (0.53) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL15611343 0.71 HTR7 (0.33) LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1393899-B1 On-press developable lithographic printing plate precursor FUJIFILM CORP (JP) 2009-07-08 EP disclosed
US-6969575-B2 On-press developable lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-11-29 US disclosed
US-20040048191-A1 On-press developable lithographic printing plate precursor FUJI PHOTO FILM CO., LTD 2004-03-11 US disclosed
EP-1393899-A2 On-press developable lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-03-03 EP disclosed