Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 12/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947691 | 0.83 | HTT (0.44) | HPGDKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL3952641 | 0.77 | ELANE (0.52) | HPGDELANEALDH1A1GAAMAPT | |
| SCHEMBL6903338 | 0.74 | HPGD (0.58) | HPGDELANECA12CA2CA9 | |
| SCHEMBL30367636 | 0.74 | HPGD (0.58) | HPGDELANECA12CA2CA9 | |
| SCHEMBL7387523 | 0.73 | ELANE (0.48) | ELANECA12CA2CA9ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL29165723 | 0.73 | HPGD (0.57) | HPGDELANECA12CA2CA9 | |
| SCHEMBL7306492 | 0.71 | ELANE (0.57) | ELANECA12CA2CA9KDM4E | |
| SCHEMBL4139429 | 0.71 | CA9 (0.36) | HPGDELANETHRBCA12CA2 | |
| SCHEMBL3947295 | 0.66 | HTT (0.45) | HPGDELANEMEN1GAAMAPT | |
| SCHEMBL24206029 | 0.65 | LMNA (0.44) | HPGDELANECA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | claimed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | claimed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | claimed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | claimed |
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | disclosed |
| EP-1655290-B1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | OREAL (FR) | 2009-04-29 | — | — | EP | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-7232839-B2 | Benzoisothiazolone compositions | L'OREAL (FR) | 2007-06-19 | — | — | US | disclosed |
| US-20060142587-A1 | Benzoisothiazolone compositions | L'OREAL (FR) | 2006-06-29 | — | — | US | disclosed |
| EP-1655290-A1 | Compositions comprising a benzoisothiazolone derivative and their use in the cosmetic field | L'OREAL (FR) | 2006-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142587-A1 | Benzoisothiazolone compositions | COL1A1, TYR, CUTA | HPGD 536/4885ELANE 106/4885THRB 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.