Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957367 | 1.00 | ATM (0.33) | ATM | |
| SCHEMBL7138699 | 0.83 | GABBR2 (0.32) | — | |
| SCHEMBL4446823 | 0.83 | GABBR2 (0.32) | — | |
| SCHEMBL5160963 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL5929582 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL4831609 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL4831634 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL4831561 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL6827611 | 0.75 | HTR2A (0.30) | — | |
| SCHEMBL4184691 | 0.75 | HTR2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | claimed |
| EP-1346977-B1 | Method for producing aryl-aminopropanols | SALTIGO GMBH (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-7553970-B2 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2009-06-30 | — | — | US | disclosed |
| US-7462731-B2 | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | NPIL PHARMACEUTICALS (UK) LIMITED (GB) | 2008-12-09 | — | — | US | disclosed |
| US-20060264641-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | BERENDES FRANK | 2006-11-23 | — | — | US | disclosed |
| US-20050272940-A1 | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | AVECIA LIMITED (GB) | 2005-12-08 | — | — | US | disclosed |
| EP-1542985-A2 | PROCESSES FOR THE PREPARATION OF HETEROCYCLIC HYDROXYAMINES AND INTERMEDIATES AND CATALYSTS FOR USE THEREIN | Avecia Limited (GB) | 2005-06-22 | — | — | EP | disclosed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | disclosed |
| WO-2004024708-A2 | PROCESSES FOR THE PREPARATION OF HETEROCYCLIC HYDROXYAMINES AND INTERMEDIATES AND CATALYSTS FOR USE THEREIN | AVECIA LIMITED (GB) | 2004-03-25 | — | — | WO | disclosed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272940-A1 | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | OXGR1, HRH3, HRH4 | ATM 4230/4885 |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | ATM 4697/4885 |
| US-20060264641-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | ATM 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.