SCHEMBL395885

SCHEMBL395885

O=C1C(Cl)=C(Cl)C(=O)N1c1ccc(OC(F)F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
HTT P42858 3/20 0.64
LMNA P02545 3/20 0.64
KMT2A Q03164 2/20 0.64
HSP90AA1 P07900 2/20 0.64
HPGD P15428 2/20 0.64
MEN1 O00255 1/20 0.64
PKM P14618 1/20 0.64
CCR6 P51684 1/20 0.64
ATM Q13315 1/20 0.64
MAPT P10636 5/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RAB9A P51151 1/20 0.42
DRD1 P21728 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
TLR9 Q9NR96 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052544 0.81 ALDH1A1 (0.44) ALDH1A1HTTLMNAKMT2AHSP90AA1
SCHEMBL28171848 0.80 KMT2A (0.61) ALDH1A1HTTLMNAKMT2AHSP90AA1
SCHEMBL8678075 0.78 HSP90AA1 (1.00) ALDH1A1HTTLMNAKMT2AHSP90AA1
SCHEMBL10929737 0.77 RAD51 (0.45) ALDH1A1HTTLMNAKMT2AMEN1
SCHEMBL10834058 0.76 MAPT (0.67) ALDH1A1HTTLMNAKMT2AHPGD
SCHEMBL6253484 0.75 MAPT (0.44) ALDH1A1HTTLMNAKMT2AHPGD
SCHEMBL11638382 0.73 MGLL (0.62) ALDH1A1HTTLMNAKMT2AHPGD
Fluoroimide SCHEMBL68964 0.72 MGLL (0.56) KMT2AMEN1GAA
SCHEMBL8504879 0.72 MEN1 (0.65) ALDH1A1KMT2AMEN1MAPTSMN1; SMN2
SCHEMBL6211924 0.71 ALDH1A1 (0.54) ALDH1A1HTTLMNAKMT2AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US claimed
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 US claimed
US-11905315-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2024-02-20 US claimed
US-20210179672-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA GENISYS CREDIT UNION 2021-06-17 US claimed
EP-2533633-B1 FUNGICIDAL MIXTURES LANXESS DISTRIB GMBH (DE) 2017-02-01 EP claimed
WO-2016044655-A2 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC. (US) 2016-03-24 WO claimed
US-20130195997-A1 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2013-08-01 US claimed
EP-2533633-A2 FUNGICIDAL MIXTURES LANXESS Distribution GmbH (DE) 2012-12-19 EP claimed
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP claimed
US-20110319435-A1 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-12-29 US claimed
WO-2011095492-A2 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-08-11 WO claimed
EP-2315522-A2 FORMATE-CONTAINING FUNGICIDE MIXTURES LANXESS Distribution GmbH (DE) 2011-05-04 EP claimed
EP-2153720-A1 Fungicide mixtures comprising formate LANXESS Distribution GmbH (DE) 2010-02-17 EP claimed
WO-2010015635-A2 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2010-02-11 WO claimed
US-4455315-A N-(Difluoromethoxy substituted phenyl)-dichloromaleimides used in agricultural and horticultural fungicidal methods SHOWA DENKO KABUSHIKI KAISHA (JP) 1984-06-19 US claimed
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes SPOGEN BIOTECH INC. (US) 2026-05-19 US disclosed
US-12599649-B2 Bioactive polypeptides for improvements in plant protection, growth and productivity SPOGEN BIOTECH INC. (US) 2026-04-14 US disclosed
WO-1997047606-A1 ARYLOXYACRYLIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed
US-4455315-A N-(Difluoromethoxy substituted phenyl)-dichloromaleimides used in agricultural and horticultural fungicidal methods SHOWA DENKO KABUSHIKI KAISHA (JP) 1984-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes ADA, RNGTT, GNPDA1 ALDH1A1 2323/4885HTT 4654/4885LMNA 3510/4885
US-12599649-B2 Bioactive polypeptides for improvements in plant protection, growth and productivity MAX, VIP, MRTO4 ALDH1A1 4854/4885HTT 1556/4885LMNA 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.