SCHEMBL8504879

SCHEMBL8504879

O=C1C(Cl)=C(Cl)C(=O)N1c1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
MGLL Q99685 1/20 0.60
POLB P06746 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
RAD51 Q06609 1/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPT P10636 1/20 0.56
ALOX12 P18054 1/20 0.56
ELANE P08246 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8718016 0.88 MEN1 (0.58) MEN1KMT2AMGLLPOLBL3MBTL1
SCHEMBL10834894 0.81 MEN1 (0.61) MEN1KMT2AMGLLPOLBL3MBTL1
Fluoroimide SCHEMBL68964 0.81 MGLL (0.56) MEN1KMT2AMGLLPOLBL3MBTL1
SCHEMBL10834478 0.81 FAAH (0.56) MEN1KMT2AMGLLPOLBL3MBTL1
SCHEMBL15347079 0.80 KMT2A (0.69) MEN1KMT2AMGLLPOLBL3MBTL1
SCHEMBL11117005 0.80 MGLL (0.60) MEN1KMT2AMGLLPOLBL3MBTL1
SCHEMBL2488181 0.80 ALDH1A1 (0.59) MEN1KMT2AMGLLL3MBTL1RAD51
SCHEMBL3627957 0.79 KMT2A (1.00) MEN1KMT2AMGLL
SCHEMBL22203806 0.79 MEN1 (0.70) MEN1KMT2AMGLLPOLBL3MBTL1
SCHEMBL4395690 0.79 FAAH (0.57) MEN1KMT2AMGLLPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830430-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-08-18 EP claimed
US-5821300-A MONOMERS INCLUDE ORGANOTIN-CONTAINING (METH)ACRYLATES AND N-SUBSTITUTED MALEIMIDES WITCO GMBH (DE) 1998-10-13 US claimed
EP-0841353-A1 Process for the preparation of polymeric binders and their application as antifouling paint Witco GmbH (DE) 1998-05-13 EP claimed
EP-0830430-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-03-25 EP claimed
WO-1996041841-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO claimed
EP-0830430-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-08-18 EP disclosed
US-5821300-A MONOMERS INCLUDE ORGANOTIN-CONTAINING (METH)ACRYLATES AND N-SUBSTITUTED MALEIMIDES WITCO GMBH (DE) 1998-10-13 US disclosed
EP-0841353-A1 Process for the preparation of polymeric binders and their application as antifouling paint Witco GmbH (DE) 1998-05-13 EP disclosed
EP-0830430-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-03-25 EP disclosed
WO-1996041841-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO disclosed
US-4563209-A ALGAE AND SHELLFISH IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1986-01-07 US disclosed
EP-0010107-B1 REPELLENT AGAINST AQUATIC ORGANISMS IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1983-04-13 EP disclosed
EP-0068822-A2 Novel heterocyclic substituted benzenes, herbicidal compositions containing them and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1983-01-05 EP disclosed
EP-0010107-A1 REPELLENT AGAINST AQUATIC ORGANISMS IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1980-04-30 EP disclosed
US-4111879-A RESIN AND AN N-ARYL-MALEIMIDE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1978-09-05 US disclosed