Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348133 | 0.78 | — | — | |
| SCHEMBL5535944 | 0.76 | NPC1 (0.37) | ALDH1A1LMNATP53NPC1RAB9A | |
| SCHEMBL3788123 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MEN1TP53KMT2ATDP1 | |
| SCHEMBL5541945 | 0.74 | TAAR1 (0.41) | ALDH1A1MEN1LMNATP53KMT2A | |
| SCHEMBL3790377 | 0.74 | MAOA (0.47) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4702413 | 0.74 | NPC1 (0.41) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5538900 | 0.72 | KIF11 (0.43) | ALDH1A1 | |
| SCHEMBL11228525 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPK1MEN1LMNATP53 | |
| SCHEMBL290676 | 0.71 | IMPDH2 (0.32) | — | |
| SCHEMBL5104622 | 0.69 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 977 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-115385955-A | Tetrabiarylphosphine ligands and transition metal complexes thereof | 东莞市均成高新材料有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-115385957-A | Linear terphenyl aryl phosphine ligand and transition metal complex thereof | 东莞市均成高新材料有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-115385956-A | Biaryl diphosphine ligands and transition metal complexes thereof | 东莞市均成高新材料有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-115028539-A | Arylamine derivative and organic electroluminescent device using same | 江苏三月科技股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-109962166-B | Organic electroluminescent device and preparation method thereof | 固安鼎材科技有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-114516804-A | Diamine derivative and organic electroluminescent device using same | 江苏三月科技股份有限公司 | 2022-05-20 | — | — | CN | claimed |
| US-RE48841-E1 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-07 | — | — | US | claimed |
| CN-109824671-B | Quinazoline triazole derivative and application thereof in organic electroluminescence field | 北京鼎材科技有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-108727389-B | Pyrene derivative and application thereof in organic luminescent material | 北京鼎材科技有限公司 | 2020-09-18 | — | — | CN | claimed |
| WO-1992018127-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS TO ENHANCE THE EFFECTS OF ANTIPSYCHOTIC DRUGS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0497843-A4 | (N-PHTHALIMIDOALKYL) PIPERIDINES | — | 1992-09-23 | — | — | EP | claimed |
| WO-1992014463-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS FOR TREATMENT OF AMPHETAMINE ABUSE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-09-03 | — | — | WO | claimed |
| WO-1992014464-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS FOR TREATMENT OF COCAINE ABUSE | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-09-03 | — | — | WO | claimed |
| EP-0497843-A1 | (N-PHTHALIMIDOALKYL) PIPERIDINES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-08-12 | — | — | EP | claimed |
| WO-1991006297-A1 | (N-PHTHALIMIDOALKYL) PIPERIDINES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-05-16 | — | — | WO | claimed |
| US-5011827-A | Elaiophyline derivatives, compositions containing them and the use thereof as anthelmintic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| US-4914090-A | Ophthalmic compositions | SCHERING CORPORATION (US) | 1990-04-03 | — | — | US | claimed |
| EP-0161211-A1 | N-heterocyclosulfonyl-N'-pyrimidinyl and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | claimed |
| US-4500494-A | POLYUREA OR UREA-FORMALDEHYDE SHELLS CONTAINING DIKETONE, 8-HYDROXYQUINOLINE OR OXIME | STAUFFER CHEMICAL COMPANY (US) | 1985-02-19 | — | — | US | claimed |