Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295065 | 0.88 | GRM5 (0.55) | GRM5MEN1MAPK10GFERKMT2A | |
| SCHEMBL7985486 | 0.83 | MAPK10 (0.61) | GRM5MEN1MAPK10GFERKMT2A | |
| SCHEMBL23799304 | 0.77 | GRM5 (0.55) | GRM5ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5582608 | 0.75 | GRM5 (1.00) | GRM5MEN1MAPK10GFERKMT2A | |
| SCHEMBL23798616 | 0.75 | GRM5 (0.54) | GRM5ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5772959 | 0.75 | GRM5 (0.58) | GRM5MEN1MAPK10GFERKMT2A | |
| SCHEMBL7985498 | 0.72 | MEN1 (0.66) | GRM5MEN1MAPK10GFERKMT2A | |
| SCHEMBL13601937 | 0.72 | GRM5 (0.51) | GRM5ALDH1A1HPGDSMN1; SMN2CYP1A2 | |
| Alcohol SCHEMBL11701443 | 0.72 | KMT2A (0.59) | GRM5MEN1MAPK10GFERKMT2A | |
| SCHEMBL23319547 | 0.72 | GRM5 (0.54) | GRM5MEN1MAPK10GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2082005-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | Pleotint, L.L.C. (US) | 2009-07-29 | — | — | EP | claimed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | claimed |
| US-8182718-B2 | Ligand exchange thermochromic systems and high ε ligands for same | PLEOTINT, L.L.C. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20080105851-A1 | Exhibiting a reversible change in absorbance of electromagnetic radiation as the temperature of the system is reversibly changed; comprising a transition metal ion and a ligand | PLEOTINT, LLC (US) | 2008-05-08 | — | — | US | disclosed |