Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960802 | 0.93 | MAPT (0.49) | MAPTTP53PPARAPPARGTRPM8 | |
| SCHEMBL3965746 | 0.91 | PPARA (0.50) | MAPTTP53PPARAPPARGTRPM8 | |
| SCHEMBL3968349 | 0.91 | PPARA (0.53) | MEN1KMT2ARAB9APPARAPPARG | |
| SCHEMBL3964675 | 0.91 | TRPM8 (0.52) | MEN1KMT2ARAB9AMAPTTP53 | |
| SCHEMBL3963635 | 0.89 | TRPM8 (0.54) | MAPTTP53PPARATRPM8POLB | |
| SCHEMBL3956888 | 0.88 | TP53 (0.53) | RAB9AMAPTTP53PPARATRPM8 | |
| SCHEMBL3963785 | 0.86 | TRPM8 (0.49) | MAPTTP53PPARAPPARGTRPM8 | |
| SCHEMBL3963868 | 0.84 | PPARA (0.54) | MEN1KMT2ARAB9AMAPTTP53 | |
| SCHEMBL3969064 | 0.84 | PPARA (0.60) | PPARAPPARG | |
| SCHEMBL3966524 | 0.83 | PPARA (0.59) | PPARAPPARGTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488844-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2009-02-10 | — | — | US | disclosed |
| US-20050282822-A1 | Therapeutic agents | ASTRAZENECA AB (SE) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282822-A1 | Therapeutic agents | GPR119, LIPC, PNLIP | MEN1 2350/4885KMT2A 4622/4885RAB9A 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.