SCHEMBL396107

SCHEMBL396107

CO[Si](CCCNC(=O)c1ccc2[nH]cnc2c1)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
HTT P42858 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
KMT2A Q03164 2/20 0.46
HDAC6 Q9UBN7 2/20 0.44
HPGD P15428 1/20 0.44
NAMPT P43490 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CASP6 P55212 1/20 0.42
HDAC1 Q13547 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396108 0.91 HTT (0.65) POLBTDP1HTTL3MBTL1NPC1
SCHEMBL13373316 0.85 HTT (0.57) POLBTDP1HTTL3MBTL1KMT2A
SCHEMBL2353678 0.85 HTT (0.57) POLBTDP1HTTL3MBTL1NPC1
SCHEMBL31047594 0.83 EPHX1 (0.58) POLBTDP1HTTL3MBTL1KMT2A
SCHEMBL31047555 0.83 EPHX1 (0.58) POLBTDP1HTTL3MBTL1KMT2A
SCHEMBL2352590 0.83 HTT (0.54) POLBTDP1HTTL3MBTL1KMT2A
SCHEMBL2352983 0.82 HTT (0.54) POLBTDP1HTTL3MBTL1NPC1
SCHEMBL6783835 0.81 HTT (0.53) POLBTDP1HTTL3MBTL1HDAC6
SCHEMBL2356085 0.81 HTT (0.53) POLBTDP1HTTL3MBTL1KMT2A
SCHEMBL5013231 0.81 BCHE (0.42) POLBTDP1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101315-B2 Hybrid membranes, method for production of hybrid membranes and fuel cells using such hybrid membranes ELCOMAX MEMBRANES GMBH (DE) 2012-01-24 US disclosed
US-20090075141-A1 HYBRID MEMBRANES, METHOD FOR PRODUCTION OF HYBRID MEMBRANES AND FUEL CELLS USING SUCH HYBRID MEMBRANES ELCOMAX MEMBRANES GMBH (DE) 2009-03-19 US disclosed