Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6832522 | 0.98 | MEN1 (0.42) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL7532656 | 0.78 | MEN1 (0.40) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL16696020 | 0.78 | MEN1 (0.40) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL15315509 | 0.78 | MEN1 (0.40) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL14340362 | 0.78 | MEN1 (0.40) | TDP1LMNAMEN1MAPTTHRB | |
| Iodide SCHEMBL5247675 | 0.76 | LMNA (0.71) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL4615881 | 0.75 | VDR (0.58) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL24967688 | 0.74 | MEN1 (0.37) | TDP1LMNAMEN1MAPTTHRB | |
| SCHEMBL559385 | 0.74 | TDP1 (0.42) | TDP1LMNAMEN1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL4613582 | 0.74 | VDR (0.57) | TDP1LMNAMEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066290-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2015-05-07 | — | — | WO | disclosed |
| WO-2009037348-A1 | INDOLINIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISNG THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |
| EP-0176472-B1 | METHINE AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-01-24 | — | — | EP | disclosed |
| US-4883866-A | DYEING PAPER | CIBA-GEIGY CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0176473-B1 | METHINE AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-07-19 | — | — | EP | disclosed |
| US-4847364-A | CATIONIC DYES FOR PAPER | CIBA SPECIALTY CHEMICALS CORPORATION | 1989-07-11 | — | — | US | disclosed |
| US-4754021-A | DYEING PAPER, POLYACRYLONITRILE, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0176472-A1 | Methine azo compounds | CIBA-GEIGY AG (CH) | 1986-04-02 | — | — | EP | disclosed |
| EP-0176474-A1 | Methine azo compounds | CIBA-GEIGY AG (CH) | 1986-04-02 | — | — | EP | disclosed |
| EP-0176473-A1 | Methine azo compounds | CIBA-GEIGY AG (CH) | 1986-04-02 | — | — | EP | disclosed |