SCHEMBL559385

SCHEMBL559385

CC1=[N+](C)c2ccc(S(=O)(=O)[O-])cc2C1(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.42
LMNA P02545 3/20 0.42
MEN1 O00255 3/20 0.37
MAPT P10636 3/20 0.37
THRB P10828 3/20 0.37
RECQL P46063 3/20 0.37
KMT2A Q03164 3/20 0.37
HTT P42858 2/20 0.37
KDM4E B2RXH2 2/20 0.37
APEX1 P27695 1/20 0.37
VDR P11473 1/20 0.32
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929178 1.00 TDP1 (0.42) TDP1LMNAMEN1MAPTTHRB
SCHEMBL5462937 0.86 LMNA (0.41) TDP1LMNAMEN1MAPTTHRB
SCHEMBL559919 0.85 LMNA (0.36) TDP1LMNAMEN1MAPTTHRB
SCHEMBL17250078 0.85 MAPT (0.42) TDP1LMNAMEN1MAPTTHRB
SCHEMBL28339818 0.83 LMNA (0.37) TDP1LMNAMEN1MAPTTHRB
SCHEMBL7740556 0.81 ACHE (0.41) TDP1LMNAMEN1MAPTTHRB
SCHEMBL2025501 0.80 LMNA (0.42) TDP1LMNAMEN1MAPTTHRB
SCHEMBL41357 0.80 LMNA (0.63) TDP1LMNAMEN1MAPTTHRB
Sulfuric Acid SCHEMBL4616814 0.78 VDR (0.52) TDP1LMNAMEN1MAPTTHRB
Sulfuric Acid SCHEMBL4614640 0.78 ESPL1 (0.43) TDP1LMNAMAPTKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024025260-A1 FLUORESCENT PROBE COMPOUND AND COMPOSITE COMPRISING SAME 한국생명공학연구원 2024-02-01 WO disclosed
US-20230219932-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-07-13 US disclosed
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 US disclosed
EP-2129788-B1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS LLC (US) 2014-09-03 EP disclosed
US-20140086844-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC (US) 2014-03-27 US disclosed
US-8642014-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2014-02-04 US disclosed
US-8552027-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2013-10-08 US disclosed
US-20120035346-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2012-02-09 US disclosed
EP-1078023-B1 LUMINESCENT COMPOUNDS LUMINEX CORPORATION (US) 2011-01-05 EP disclosed
US-20100266507-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2010-10-21 US disclosed
US-20030235846-A1 Luminescent compounds TERPTETSCHNIG, EWALD A. 2003-12-25 US disclosed
EP-1078023-A4 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 2003-03-26 EP disclosed
US-6538129-B1 Luminescent compounds Terpetschnig, Ewald A. 2003-03-25 US disclosed
US-6441191-B1 INFRARED ABSORBING AGENTS IN COLLOIDAL LAYERS FOR PHOTOGRAPHIC RECORDING MATERIALS; LONG WAVELENGTH; INTENSE ABSORPTION HONEYWELL INTERNATIONAL INC. 2002-08-27 US disclosed
US-6261753-B1 INFRARED RADIATION ABSORBERS; PHOTOGRAPHIC RECORDING MATERIALS RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 2001-07-17 US disclosed
EP-1078023-A1 LUMINESCENT COMPOUNDS Terpetschnig, Ewald A. (US) 2001-02-28 EP disclosed
EP-0694586-B1 Use of indoleninecyaninedisulfonic acid derivatives as infrared absorbing compounds RIEDEL DE HAEN GMBH (DE) 2000-04-19 EP disclosed
WO-1999051702-A1 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 1999-10-14 WO disclosed
US-5747233-A INFRARED ABSORBERS AND PHOTOGRAPHY RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1998-05-05 US disclosed
EP-0694586-A1 Use of indoleninecyaninedisulfonic acid derivatives as infrared absorbing compounds RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1996-01-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100266507-A1 LUMINESCENT COMPOUNDS SQLE, COASY, ZKSCAN2 TDP1 4554/4885LMNA 985/4885MEN1 1430/4885
US-20140086844-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS TDP1 1854/4885LMNA 986/4885MEN1 1189/4885
US-20030235846-A1 Luminescent compounds CROCC, NR2E1, NDC1 TDP1 4472/4885LMNA 813/4885MEN1 4116/4885
US-20230219932-A1 COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME BMP1, BMP2, NPSR1 TDP1 4538/4885LMNA 2583/4885MEN1 387/4885
US-20120035346-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS TDP1 2133/4885LMNA 1037/4885MEN1 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.