Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12453354 | 0.79 | MEN1 (0.69) | LMNAMEN1MAPTTHRBHTT | |
| Iodide SCHEMBL3852244 | 0.78 | MAPT (0.68) | LMNAMEN1MAPTTHRBHTT | |
| Iodide SCHEMBL6832522 | 0.78 | MEN1 (0.42) | LMNAMEN1MAPTTHRBHTT | |
| SCHEMBL16867351 | 0.76 | MEN1 (0.65) | LMNAMEN1MAPTTHRBHTT | |
| SCHEMBL4617512 | 0.76 | MAPT (0.65) | LMNAMEN1MAPTTHRBHTT | |
| SCHEMBL3961483 | 0.76 | TDP1 (0.40) | LMNAMEN1MAPTTHRBHTT | |
| Iodide SCHEMBL2320529 | 0.76 | MAPT (0.65) | LMNAMEN1MAPTTHRBHTT | |
| Iodide SCHEMBL29658781 | 0.76 | MAPT (0.65) | LMNAMEN1MAPTTHRBHTT | |
| Bromide SCHEMBL4615096 | 0.75 | MAPT (0.63) | LMNAMEN1MAPTTHRBHTT | |
| SCHEMBL41357 | 0.75 | LMNA (0.63) | LMNAMEN1MAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223196-B1 | Negative image-recording material and cyanine dye | FUJIFILM CORP (JP) | 2007-09-12 | — | — | EP | disclosed |
| US-6797449-B2 | FOR PLANOGRAPHIC PRINTING PLATE PRECURSORS, COLOR PROOFS, PHOTORESISTS AND COLOR FILTERS; HIGH INFRARED RADIATION ABSORPTION; SEMICONDUCTOR LASERS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| US-20030022094-A1 | For planographic printing plate precursors, color proofs, photoresists and color filters; high infrared radiation absorption; semiconductor lasers | FUJIFILM CORPORATION (JP) | 2003-01-30 | — | — | US | disclosed |
| EP-1223196-A2 | Negative image-recording material and cyanine dye | Fuji Photo Film Co., Ltd. (JP) | 2002-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022094-A1 | For planographic printing plate precursors, color proofs, photoresists and color filters; high infrared radiation absorption; semiconductor lasers | MARK4, MARK3, IK | LMNA 3401/4885MEN1 3630/4885MAPT 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.