Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77874 | 0.82 | ACHE (0.45) | BCHECHRM2ALDH1A1MAPTKDM4E | |
| SCHEMBL11063357 | 0.82 | KIF11 (0.54) | BCHECHRM2ALDH1A1KIF11TRPV1 | |
| SCHEMBL11801182 | 0.80 | MAPT (0.54) | BCHECHRM2ALDH1A1MAPTKDM4E | |
| SCHEMBL17549812 | 0.80 | BCHE (0.48) | BCHECHRM2ALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL6851422 | 0.78 | MAPT (0.53) | BCHECHRM2ALDH1A1MAPTKDM4E | |
| SCHEMBL12893245 | 0.77 | ALDH1A1 (0.51) | BCHEALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL5494529 | 0.75 | EPHX2 (0.53) | ALDH1A1KIF11MAPTPOLBKMT2A | |
| SCHEMBL25612493 | 0.74 | ESR1 (0.53) | BCHECHRM2ALDH1A1MAPTKDM4E | |
| SCHEMBL19490759 | 0.74 | BCHE (0.50) | BCHECHRM2MAPTNPC1RAB9A | |
| SCHEMBL15314351 | 0.73 | BCHE (0.43) | BCHECHRM2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036235-A2 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (ACHE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2009-03-19 | — | — | WO | claimed |