Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3957512 | 0.95 | HTR6 (0.64) | HTR6POLBPAX8LMNASLC6A9 | |
| SCHEMBL3147704 | 0.82 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3142917 | 0.78 | HTR6 (0.85) | HTR6SLC6A9NTSR1NR1I2 | |
| SCHEMBL4037350 | 0.76 | HTR6 (1.00) | HTR6SLC6A9NTSR1NR1I2 | |
| SCHEMBL3153226 | 0.76 | HTR6 (0.74) | HTR6SLC6A9NTSR1NR1I2 | |
| SCHEMBL3153146 | 0.74 | HTR6 (1.00) | HTR6 | |
| SCHEMBL6270103 | 0.72 | HTR6 (0.55) | HTR6SLC6A9NR1I2 | |
| SCHEMBL6273953 | 0.71 | SLC6A9 (0.55) | HTR6SLC6A9 | |
| SCHEMBL13106713 | 0.69 | HTR6 (0.58) | HTR6NTSR1NR1I2 | |
| Hydrochloric Acid SCHEMBL11101542 | 0.69 | ALOX15 (0.64) | HTR6SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | claimed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | claimed |
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009036955-A1 | NAPHTYL-SUBSTITUTED SULFONAMIDES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-03-26 | — | — | WO | disclosed |
| EP-2036888-A1 | Naphthyl-substituted sulfonamides | Laboratorios del Dr. Esteve S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |