Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.55 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273953 | 0.99 | SLC6A9 (0.55) | HTR6SLC6A9TSHRGAAALDH1A1 | |
| SCHEMBL6273962 | 0.74 | GAA (0.59) | TSHRGAAALDH1A1HTT | |
| SCHEMBL6269857 | 0.74 | TSHR (0.59) | TSHRGAAALDH1A1HTT | |
| SCHEMBL3961769 | 0.72 | HTR6 (0.69) | HTR6SLC6A9NR1I2 | |
| SCHEMBL6270957 | 0.71 | GAA (0.56) | TSHRGAAALDH1A1 | |
| SCHEMBL27082080 | 0.71 | HTR6 (0.58) | HTR6TSHRHTTPGRRORA | |
| SCHEMBL3147704 | 0.71 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3142917 | 0.71 | HTR6 (0.85) | HTR6SLC6A9NR1I2 | |
| SCHEMBL4037350 | 0.71 | HTR6 (1.00) | HTR6SLC6A9NR1I2 | |
| SCHEMBL3259317 | 0.71 | ALDH1A1 (0.64) | TSHRALDH1A1HTTPFKFB3HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245561-B1 | N-SUBSTITUTED BENZYL OR PHENYL AROMATIC SULFAMIDES COMPOUNDS AND THE USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2005-12-28 | — | — | EP | claimed |
| US-6605635-B1 | Prevention and treatment of cardiac arrhythmia; condensation of aromatic sulfochloride with p-hydroxybenzylamine followed by mannich reaction | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCE (CN) | 2003-08-12 | — | — | US | claimed |