Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455572 | 0.83 | NAPRT (0.63) | NAPRTLMNASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL2409306 | 0.81 | NAPRT (0.61) | NAPRTLMNASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL3432130 | 0.81 | NAPRT (0.61) | NAPRTLMNASMN1; SMN2CTNNB1WNT3A | |
| Bromide SCHEMBL4126411 | 0.80 | NAPRT (0.59) | NAPRTLMNASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL9696312 | 0.79 | ALDH1A1 (0.50) | NAPRTLMNASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL429687 | 0.79 | NAPRT (0.68) | NAPRTLMNASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL27612856 | 0.78 | NAPRT (0.73) | NAPRTLMNASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL11134348 | 0.78 | NAPRT (0.61) | NAPRTLMNASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL4970018 | 0.78 | P2RX7 (0.59) | LMNASMN1; SMN2CTNNB1WNT3AKMT2A | |
| SCHEMBL7371695 | 0.77 | NAPRT (0.61) | NAPRTSMN1; SMN2CTNNB1WNT3AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035855-A2 | NOVEL USES OF HALOGENATED ALKYL SULFONAMIDES | H. LUNDBECK A/S (DK) | 2009-03-19 | — | — | WO | disclosed |
| WO-2007103295-A2 | HALOGENATED SULFONAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213376-A1 | Halogenated sulfonamide derivatives | H. LUNDBECK A/S (DK) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213376-A1 | Halogenated sulfonamide derivatives | NPY5R, NPY2R, SSTR5 | NAPRT 2817/4885LMNA 4530/4885SMN1; SMN2 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.