Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316937 | 1.00 | CES2 (0.49) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL4446826 | 1.00 | CES2 (0.49) | CES2CES1KEAP1RAB9ANPC1 | |
| Ethane SCHEMBL4831611 | 0.96 | CES2 (0.46) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL27571074 | 0.83 | ALOX5 (0.47) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL13988109 | 0.83 | CES2 (0.47) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL1200875 | 0.83 | ALOX5 (0.47) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL658090 | 0.82 | CES2 (0.46) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL26820640 | 0.82 | MGAM (0.54) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL26820652 | 0.82 | MGAM (0.54) | CES2CES1KEAP1RAB9ANPC1 | |
| SCHEMBL6499256 | 0.81 | NPC1 (0.48) | CES2CES1KEAP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | claimed |
| CN-121735899-A | Preparation method and application of (S) -3-hydroxy-3- (2-thienyl) -propionate compound | 浙江华海药业股份有限公司 | 2026-03-27 | — | — | CN | disclosed |
| CN-105039361-B | Carbonyl reduction enzyme gene, codase, carrier, bacterial strain and application | 浙江工业大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-105039361-A | Carbonyl reductase gene, codase, vector, strain and application of gene | UNIV ZHEJIANG TECHNOLOGY | 2015-11-11 | — | — | CN | disclosed |
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| CN-102191293-A | Method for inversing microbe to prepare ethyl (S)-3-hydroxy-3-(2-thienyl)-propanoate | UNIV ZHEJIANG TECHNOLOGY | 2011-09-21 | — | — | CN | disclosed |
| CN-102191293-A | Method for inversing microbe to prepare ethyl (S)-3-hydroxy-3-(2-thienyl)-propanoate | UNIV ZHEJIANG TECHNOLOGY | 2011-09-21 | — | — | CN | disclosed |
| CN-102191293-A | Method for inversing microbe to prepare ethyl (S)-3-hydroxy-3-(2-thienyl)-propanoate | UNIV ZHEJIANG TECHNOLOGY | 2011-09-21 | — | — | CN | disclosed |
| US-20090286997-A1 | PROCESS FOR PREPARING ARYLAMINOPROPANOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| US-7582776-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-1346977-B1 | Method for producing aryl-aminopropanols | SALTIGO GMBH (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-7553970-B2 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2009-06-30 | — | — | US | disclosed |
| US-20080262247-A1 | Process for preparing arylaminopropanols | ECKERT MARKUS | 2008-10-23 | — | — | US | disclosed |
| US-7169938-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-01-30 | — | — | US | disclosed |
| US-20060264641-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | BERENDES FRANK | 2006-11-23 | — | — | US | disclosed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | disclosed |
| EP-1405917-A2 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | Bayer Chemicals AG (DE) | 2004-04-07 | — | — | EP | disclosed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | CES2 165/4885CES1 878/4885KEAP1 939/4885 |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | CES2 888/4885CES1 188/4885KEAP1 1100/4885 |
| US-20090286997-A1 | PROCESS FOR PREPARING ARYLAMINOPROPANOLS | AHR, CYP1A1, CYP1A2 | CES2 165/4885CES1 878/4885KEAP1 939/4885 |
| US-20080262247-A1 | Process for preparing arylaminopropanols | CYP1A1, CYP1A2, AHR | CES2 127/4885CES1 723/4885KEAP1 961/4885 |
| US-20060264641-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | CES2 888/4885CES1 188/4885KEAP1 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.