Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 7/20 | 0.36 |
| ▸ | MMP13 | P45452 | 7/20 | 0.36 |
| ▸ | MMP3 | P08254 | 6/20 | 0.36 |
| ▸ | MMP9 | P14780 | 6/20 | 0.36 |
| ▸ | MMP8 | P22894 | 6/20 | 0.36 |
| ▸ | MMP14 | P50281 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 3/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CCR7 | P32248 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962562 | 0.88 | ALDH1A1 (0.39) | MMP13MMP9MMP1KMT2AMEN1 | |
| SCHEMBL1464393 | 0.81 | MMP2 (0.44) | MLYCDMMP2MMP13MMP3MMP9 | |
| SCHEMBL1464260 | 0.79 | MMP2 (0.49) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3962907 | 0.78 | MAPT (0.37) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3969923 | 0.77 | ALDH1A1 (0.40) | KMT2AMEN1NPSR1MAPT | |
| SCHEMBL3967700 | 0.75 | MMP2 (0.47) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3961452 | 0.75 | MMP2 (0.45) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3963997 | 0.75 | KMT2A (0.60) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL1464281 | 0.74 | MMP2 (0.51) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3963998 | 0.72 | GCK (0.45) | MMP2MMP13MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |