Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963271 | 1.00 | CYP2A6 (0.43) | CYP2A6CYP2C9CYP2B6CYP2C19CYP3A4 | |
| SCHEMBL2014183 | 0.76 | CYP11B2 (0.61) | CYP2A6CYP2C9CYP2B6CYP2C19CYP3A4 | |
| Water SCHEMBL4803706 | 0.76 | CYP11B2 (0.61) | CYP2A6CYP2C9CYP2B6CYP2C19CYP3A4 | |
| SCHEMBL29434996 | 0.76 | — | — | |
| Water SCHEMBL28116587 | 0.76 | — | — | |
| SCHEMBL28776 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6439131 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL22031517 | 0.74 | CYP11B2 (0.59) | CYP2A6CYP2C9CYP2B6CYP2C19CYP3A4 | |
| Benzene SCHEMBL15416232 | 0.74 | CYP11B2 (0.59) | CYP2A6CYP2C9CYP2B6CYP2C19CYP3A4 | |
| Bromide SCHEMBL9901166 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| CN-1250519-C | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2006-04-12 | — | — | CN | disclosed |
| CN-1250518-C | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2006-04-12 | — | — | CN | disclosed |
| CN-1205175-C | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2005-06-08 | — | — | CN | disclosed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | disclosed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | disclosed |
| CN-1415596-A | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | disclosed |
| CN-1365967-A | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | disclosed |
| CN-1365966-A | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | KCNMA1, KCNA5, KCNA1 | CYP2A6 1459/4885CYP2C9 1466/4885CYP2B6 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.