Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960763 | 0.93 | MEN1 (0.38) | RORCCNR2CNR1ALDH1A1MAPT | |
| SCHEMBL3963986 | 0.89 | CNR2 (0.43) | CNR2CNR1ALDH1A1MAPTHSD11B1 | |
| SCHEMBL1465949 | 0.82 | RORC (0.56) | RORCCNR2CNR1ALDH1A1HSD17B10 | |
| SCHEMBL1463796 | 0.79 | CNR2 (0.52) | RORCCNR2CNR1HSD11B1 | |
| SCHEMBL1466192 | 0.78 | ALDH1A1 (0.60) | RORCCNR2CNR1ALDH1A1HSD17B10 | |
| SCHEMBL3966458 | 0.77 | CNR2 (0.49) | RORCCNR2CNR1HSD11B1 | |
| SCHEMBL3967901 | 0.76 | FFAR2 (0.49) | CNR2CNR1HSD11B1 | |
| SCHEMBL1464685 | 0.75 | RORC (0.57) | RORCCNR2CNR1ALDH1A1HSD17B10 | |
| SCHEMBL1465040 | 0.74 | HSD11B1 (0.55) | CNR2CNR1HSD11B1 | |
| SCHEMBL1465448 | 0.72 | ALDH1A1 (0.56) | RORCALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |