Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619865 | 0.87 | KMT2A (0.57) | SMN1; SMN2ALDH1A1KMT2AMEN1EPHX2 | |
| SCHEMBL17842262 | 0.86 | RAB9A (0.75) | SMN1; SMN2ALDH1A1KMT2AMEN1MTNR1A | |
| SCHEMBL8640087 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1KMT2AMEN1MTNR1A | |
| SCHEMBL8639322 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1KMT2AMEN1EPHX2 | |
| SCHEMBL8773761 | 0.82 | MEN1 (0.54) | SMN1; SMN2ALDH1A1KMT2AMEN1EPHX2 | |
| SCHEMBL13745650 | 0.81 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1KMT2AMEN1EPHX2 | |
| SCHEMBL8641864 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1KMT2AMEN1MTNR1A | |
| SCHEMBL8928243 | 0.80 | MTNR1A (0.68) | SMN1; SMN2ALDH1A1KMT2AMEN1MTNR1A | |
| SCHEMBL8635989 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KMT2AMEN1EPHX2 | |
| SCHEMBL3963855 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KMT2AMEN1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869792-A4 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0869792-A2 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023216-A1 | 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |