Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964257 | 1.00 | VCP (0.49) | VCPCYP2A6LMNAHTTMAPT | |
| SCHEMBL3959576 | 0.77 | MAPT (0.40) | VCPMAPTALDH1A1TLR4TLR2 | |
| SCHEMBL3959578 | 0.77 | MAPT (0.40) | VCPMAPTALDH1A1TLR4TLR2 | |
| SCHEMBL11858113 | 0.77 | FBP1 (0.43) | LMNAHTTMAPTALDH1A1MEN1 | |
| SCHEMBL3956325 | 0.71 | TLR4 (0.48) | VCPMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3956322 | 0.71 | TLR4 (0.48) | VCPMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3963701 | 0.70 | KDM4E (0.37) | LMNAMAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL3963703 | 0.70 | KDM4E (0.37) | LMNAMAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL29463713 | 0.69 | — | — | |
| SCHEMBL38181 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | disclosed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | KCNMA1, KCNA5, KCNA1 | VCP 1922/4885CYP2A6 1459/4885LMNA 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.