Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994257 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAACYP3A4USP2 | |
| SCHEMBL2027850 | 0.82 | ERN1 (0.43) | MEN1KMT2AGAACYP3A4USP2 | |
| SCHEMBL12581613 | 0.80 | CYP3A4 (0.42) | MEN1KMT2AGAACYP3A4USP2 | |
| SCHEMBL5342671 | 0.79 | HTT (0.39) | CYP3A4USP2BACE1ERN1MAPT | |
| SCHEMBL3970026 | 0.77 | MAPK1 (0.53) | MEN1KMT2AGAACYP3A4OPRM1 | |
| SCHEMBL5195249 | 0.74 | ALOX15 (0.50) | MEN1KMT2AGAACYP3A4TRPA1 | |
| SCHEMBL952993 | 0.74 | ERN1 (0.38) | MEN1KMT2ACYP3A4USP2ERN1 | |
| SCHEMBL2174289 | 0.74 | TRPA1 (0.48) | MEN1KMT2AGAATRPA1BACE1 | |
| SCHEMBL1988566 | 0.72 | TRPA1 (0.46) | MEN1KMT2AGAATRPA1BACE1 | |
| SCHEMBL992788 | 0.72 | TRPA1 (0.46) | MEN1KMT2AGAATRPA1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992630-B1 | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | TICONA GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-1480987-B1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | CELANESE HOLDING GMBH (DE) | 2009-07-29 | — | — | EP | disclosed |
| EP-1992630-A1 | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | Celanese Holding GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |
| CN-100354283-C | Covalently fixed non-metallocenes, method for the production thereof and their use for polymerizing olefins | CELANESE VENTURES GMBH (DE) | 2007-12-12 | — | — | CN | disclosed |
| US-7157398-B2 | Covalently fixed nonmetallocenes, process for preparing them and their use for the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2007-01-02 | — | — | US | disclosed |
| CN-1642962-A | Covalently bound non-metallocenes, method for the production thereof and use thereof in the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2005-07-20 | — | — | CN | disclosed |
| US-20050148461-A1 | Covalently fixed nonmetallocenes, process for preparing them and their use for the polymerization of olefins | CELANESE VENTURES GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| US-6872843-B2 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| EP-1480987-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | Celanese Ventures GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | EQUISTAR CHEMICALS, LP | 2004-02-05 | — | — | US | disclosed |
| WO-2003072584-A1 | COVALENTLY FIXED NON-METALLOCENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023940-A1 | Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins | SOAT2, NOTUM, SOAT1 | MEN1 916/4885KMT2A 1566/4885GAA 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.