Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195249 | 0.81 | ALOX15 (0.50) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL992788 | 0.79 | TRPA1 (0.46) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL1988566 | 0.79 | TRPA1 (0.46) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL4629908 | 0.77 | TRPA1 (0.45) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL27351642 | 0.77 | TRPA1 (0.45) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL1187136 | 0.77 | TRPA1 (0.45) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL581480 | 0.77 | GABRA1 (0.52) | TRPA1BACE1HSPA5ALOX15ALOX12 | |
| SCHEMBL2172071 | 0.76 | TRPA1 (0.48) | TRPA1HSPA5CNR2CNR1MEN1 | |
| SCHEMBL6537139 | 0.76 | HSD17B1 (0.49) | BACE1ALOX15ALOX12MEN1GAA | |
| SCHEMBL17732232 | 0.76 | ALDH1A1 (0.42) | TRPA1BACE1HSPA5ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315435-B2 | Method for producing hydroxyphenylcyclohexanol compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-19 | — | — | US | disclosed |
| US-20150141707-A1 | METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2842930-A1 | METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
| EP-2346887-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | Dow Technology Investments LLC (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010042313-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141707-A1 | METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND | HSD11B2, CYP21A2, CYP11B2 | TRPA1 2672/4885BACE1 852/4885HSPA5 3097/4885 |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | TRPA1 1876/4885BACE1 4364/4885HSPA5 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.