SCHEMBL3965517

SCHEMBL3965517

O=c1oc(=O)c2c1ccc1c2ccc2c(=O)oc(=O)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.43
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ESR2 Q92731 12/20 0.41
ESR1 P03372 10/20 0.41
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 2/20 0.36
BLM P54132 2/20 0.36
HIF1A Q16665 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MGAM O43451 1/20 0.36
NR1I2 O75469 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305025 0.91 TDP1 (0.43) CES1TDP1L3MBTL1ESR2ESR1
SCHEMBL30027101 0.91 TDP1 (0.43) CES1TDP1L3MBTL1ESR2ESR1
SCHEMBL150550 0.88 TDP1 (0.45) CES1TDP1L3MBTL1ESR2ESR1
SCHEMBL5574162 0.86 L3MBTL1 (0.41) CES1TDP1L3MBTL1ESR2ESR1
SCHEMBL21173940 0.82 CES1 (0.47) CES1TDP1L3MBTL1ESR2BCHE
SCHEMBL22504835 0.81 TDP1 (0.47) CES1TDP1L3MBTL1ESR2ESR1
SCHEMBL6720013 0.81 CES1 (0.43) CES1TDP1L3MBTL1ESR2BCHE
SCHEMBL20963080 0.81 ALDH1A1 (0.46) TDP1L3MBTL1ESR2ALDH1A1LMNA
SCHEMBL12110767 0.79 TDP1 (0.42) CES1TDP1L3MBTL1ESR2ESR1
SCHEMBL9400336 0.78 ALDH1A1 (0.38) CES1TDP1L3MBTL1ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975741-B1 Semi-conductive polyimide film NITTO DENKO CORP (JP) 2016-01-06 EP claimed
WO-2021125308-A1 RELEASE LAYER FORMING COMPOSITION 日産化学株式会社 2021-06-24 WO disclosed
US-20210189126-A1 DETACHABLE LAYER-FORMING COMPOSITION AND DETACHABLE LAYER NISSAN CHEMICAL CORPORATION (JP) 2021-06-24 US disclosed
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer JNC CORPORATION (JP) 2021-04-06 US disclosed
US-20200317963-A1 DETACHABLE LAYER-FORMING COMPOSITION AND DETACHABLE LAYER NISSAN CHEMICAL CORPORATION (JP) 2020-10-08 US disclosed
US-10647851-B2 1,2,5,6-Naphthalenediimide co-polymer PHILLIPS 66 COMPANY (US) 2020-05-12 US disclosed
US-20190127643-A1 LIQUID CRYSTAL ALIGNING AGENT FOR PHOTOALIGNMENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE USING IT, AND DIAMINE AND POLYMER JNC CORPORATION (JP) 2019-05-02 US disclosed
WO-2019023022-A1 A 1,2,5,6-NAPHTHALENEDIIMIDE CO-POLYMER PHILLIPS 66 COMPANY (US) 2019-01-31 WO disclosed
WO-2019023021-A1 SYNTHESIS OF A 1, 2, 5, 6-NAPHTHALENEDIIMIDE MONOMER PHILLIPS 66 COMPANY (US) 2019-01-31 WO disclosed
US-20190031671-A1 SYNTHESIS OF A 1,2,5,6-NAPHTHALENEDIIMIDE MONOMER PHILLIPS 66 COMPANY (US) 2019-01-31 US disclosed
US-20070189672-A1 Method for Preparing Polymeric Optical Waveguide Device HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-08-16 US disclosed
US-20070106057-A1 Polyimide resin, method of producing polyimide resin, and electrolyte membrane, catalyst layer, membrane/electrode assembly and device each containing polyimide resin YAMANASHI, UNIVERSITY OF (JP) 2007-05-10 US disclosed
US-20070106057-A1 Polyimide resin, method of producing polyimide resin, and electrolyte membrane, catalyst layer, membrane/electrode assembly and device each containing polyimide resin YAMANASHI, UNIVERSITY OF (JP) 2007-05-10 US disclosed
US-7160356-B2 Dithiolene functionalized polymer membrane for olefin/paraffin separation BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-01-09 US disclosed
US-7160356-B2 Dithiolene functionalized polymer membrane for olefin/paraffin separation BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-01-09 US disclosed
US-6810181-B2 LAYER OF A FLUORINE-CONTAINING POLYIMIDE AND A LAYER OF A FLUORINE-FREE RESIN IS INTERPOSED BETWEEN THE POLYIMIDE LAYER AND THE ELECTRODE HITACHI CHEMICAL CO., LTD. (JP) 2004-10-26 US disclosed
US-20040096161-A1 Electrode structure HITACHI CHEMICAL CO., LTD. (JP) 2004-05-20 US disclosed
US-6638707-B2 Image forming layer containing an organic silver salt; either the image forming layer or the interlayer contains an alkoxy silane compound having at least two primary or secondary amino groups or Schiff base formed by reaction with a ketone KONICA CORPORATION (JP) 2003-10-28 US disclosed
US-20030044738-A1 Photothermographic material KONICA CORPORATION (JP) 2003-03-06 US disclosed
EP-1271235-A1 Photothermographic material KONICA CORPORATION (JP) 2003-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer DDT, DCLRE1A, DVL1 CES1 4788/4885TDP1 188/4885L3MBTL1 1272/4885
US-20190031671-A1 SYNTHESIS OF A 1,2,5,6-NAPHTHALENEDIIMIDE MONOMER NDC1, NUCB2, NOC2L CES1 2632/4885TDP1 1308/4885L3MBTL1 4169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.