SCHEMBL5574162

SCHEMBL5574162

O=c1oc(=O)c2ccc3c4ccc1c1ccc5c(=O)oc(=O)c6ccc(c5c14)c3c26

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GMNN O75496 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
ELANE P08246 1/20 0.38
CTSG P08311 1/20 0.38
CTSA P10619 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
CYP2C19 P33261 1/20 0.38
THPO P40225 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150550 0.91 TDP1 (0.45) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL3965517 0.86 CES1 (0.43) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL20963080 0.85 ALDH1A1 (0.46) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL30027101 0.82 TDP1 (0.43) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL1305025 0.82 TDP1 (0.43) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL204369 0.80 TDP1 (0.47) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL13570169 0.79 TDP1 (0.42) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL6720013 0.79 CES1 (0.43) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL29599746 0.74 NPSR1 (0.57) L3MBTL1TDP1ALDH1A1NPSR1LMNA
SCHEMBL28252904 0.74 NPSR1 (0.57) L3MBTL1TDP1ALDH1A1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070157873-A1 Method of fabrication and device comprising elongated nanosize elements KOBENHAVNS UNIVERSITET (DK) 2007-07-12 US claimed
EP-1678741-A1 METHOD OF FABRICATION AND DEVICE COMPRISING ELONGATED NANOSIZE ELEMENTS Kobenhavns Universitet (DK) 2006-07-12 EP claimed
WO-2005027201-A1 METHOD OF FABRICATION AND DEVICE COMPRISING ELONGATED NANOSIZE ELEMENTS Københavns Universitet (DK) 2005-03-24 WO claimed
US-20070157873-A1 Method of fabrication and device comprising elongated nanosize elements KOBENHAVNS UNIVERSITET (DK) 2007-07-12 US disclosed
EP-1678741-A1 METHOD OF FABRICATION AND DEVICE COMPRISING ELONGATED NANOSIZE ELEMENTS Kobenhavns Universitet (DK) 2006-07-12 EP disclosed
WO-2005027201-A1 METHOD OF FABRICATION AND DEVICE COMPRISING ELONGATED NANOSIZE ELEMENTS Københavns Universitet (DK) 2005-03-24 WO disclosed