Sugi Predict

Sugi Predict / Compounds / SCHEMBL1617437

SCHEMBL1617437

SCHEMBL1617437

CCOC(=O)C1CCCC(Br)C1=O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TLR4 O00206 1/20 0.49
▸ ALDH1A1 P00352 7/20 0.43
▸ KMT2A Q03164 5/20 0.43
▸ MAPT P10636 4/20 0.43
▸ MEN1 O00255 4/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ LMNA P02545 1/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5791081 0.90 ALDH1A1 (0.45) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL4077853 0.88 TLR4 (0.55) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL5659584 0.81 TLR4 (0.50) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL11782843 0.81 CYP1A2 (0.38) TLR4ALDH1A1HSD17B10KDM4ESMN1; SMN2
SCHEMBL14877461 0.81 GAA (0.37) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL8187713 0.80 TLR4 (0.49) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL4080364 0.80 ALDH1A1 (0.51) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL25014921 0.79 TLR4 (0.48) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL5896856 0.78 TLR4 (0.47) TLR4ALDH1A1KMT2AMAPTMEN1
SCHEMBL3362070 0.77 CYP1A2 (0.38) ALDH1A1HSD17B10KDM4ESMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729510-A1 INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Suzhou Merna Therapeutics Co. Ltd (CN) 2026-04-22 — — EP disclosed
US-20260034093-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2026-02-05 — — US disclosed
US-20250290137-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LIMITED (GB) 2025-09-18 — — US disclosed
US-12351871-B2 Substituted coumarin dyes and uses as fluorescent labels ILLUMINA CAMBRIDGE LIMITED (GB) 2025-07-08 — — US disclosed
WO-2025124365-A1 CRYSTAL FORM OF RNA M6A REGULATOR, PREPARATION METHOD FOR CRYSTAL FORM AND USE THEREOF 苏州湃芮生物科技有限公司 2025-06-19 — — WO disclosed
CN-120136769-A Crystalline form of RNA m6A modulator, and preparation method and application thereof 苏州湃芮生物科技有限公司 2025-06-13 — — CN disclosed
CN-120118019-A Eutectic form of RNA m6A modulator and preparation method and application thereof 苏州湃芮生物科技有限公司 2025-06-10 — — CN disclosed
WO-2025007928-A1 INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州湃芮生物科技有限公司 2025-01-09 — — WO disclosed
US-20240358675-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2024-10-31 — — US disclosed
US-20240271209-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LIMITED (GB) 2024-08-15 — — US disclosed
US-4423056-A 5(Aminomethyl)-4,5,6,7-tetrahydro[d]thiazole containing compositions for and medical use in treating circulatory insufficiencies LABORATOIRES JACQUES LOGEAIS (FR) 1983-12-27 — — US disclosed
US-4337343-A INCREASES CIRCULATION LABORATOIRES JACQUES LOGEAIS (FR) 1982-06-29 — — US disclosed
US-4107165-A ANTICOAGULANTS ENDO LABORATORIES (US) 1978-08-15 — — US disclosed
US-4057640-A ANTIINFLAMMATORY SCHERING AKTIENGESELLSCHAFT (DT) 1977-11-08 — — US disclosed
US-3988444-A Novel thiazole derivatives as insecticides and acaricides ROUSSEL-UCLAF (FR) 1976-10-26 — — US disclosed
US-3979391-A 1,2,3,4-Tetrahydrocarbazoles STERLING DRUG INC. (US) 1976-09-07 — — US disclosed
US-3956295-A ANTIINFLAMMATORY SCHERING AKTIENGESELLSCHAFT (DT) 1976-05-11 — — US disclosed
US-3948939-A 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids STERLING DRUG INC. (US) 1976-04-06 — — US disclosed
US-3939177-A 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles STERLING DRUG INC. (US) 1976-02-17 — — US disclosed
US-3932433-A ACRACIDES ROUSSEL-UCLAF (FR) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358675-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF GRIN2C, NLN, COMT TLR4 3995/4885ALDH1A1 919/4885KMT2A 2379/4885
US-20250290137-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS FBL, DUT, PHAX TLR4 2021/4885ALDH1A1 475/4885KMT2A 3586/4885
US-20240271209-A1 SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS FBL, DUT, PHAX TLR4 2021/4885ALDH1A1 475/4885KMT2A 3586/4885
US-12351871-B2 Substituted coumarin dyes and uses as fluorescent labels FBL, DUT, PHAX TLR4 2021/4885ALDH1A1 475/4885KMT2A 3586/4885
US-20260034093-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SLC6A3, SLC6A11, SLC6A13 TLR4 938/4885ALDH1A1 1362/4885KMT2A 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.