Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972720 | 0.86 | SMN1; SMN2 (0.69) | KMT2ASMN1; SMN2CFDTPSB2CYP4F2 | |
| SCHEMBL3964184 | 0.86 | KMT2A (0.55) | KMT2ASMN1; SMN2CFDTPSB2CYP4F2 | |
| SCHEMBL3967162 | 0.86 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2CFDTPSB2 | |
| SCHEMBL3969178 | 0.85 | SMN1; SMN2 (0.54) | KMT2ASMN1; SMN2CFDTPSB2CYP4F2 | |
| SCHEMBL15137119 | 0.85 | KMT2A (0.54) | KMT2ASMN1; SMN2CFDTPSB2CYP4F2 | |
| SCHEMBL3972169 | 0.84 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2CFDTPSB2 | |
| SCHEMBL3964418 | 0.84 | KMT2A (0.53) | KMT2ASMN1; SMN2CFDTPSB2CYP4F2 | |
| SCHEMBL3966429 | 0.81 | TDP1 (0.44) | KMT2ASMN1; SMN2CFDTPSB2 | |
| SCHEMBL3972478 | 0.81 | CHEK2 (0.42) | KMT2ASMN1; SMN2CFDTPSB2 | |
| SCHEMBL24527656 | 0.80 | PTGS1 (0.50) | KMT2ASMN1; SMN2CFDTPSB2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |