Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966610 | 1.00 | HCAR2 (0.52) | HCAR2MAPTATMNPSR1CA12 | |
| SCHEMBL20396202 | 0.86 | HCAR2 (0.57) | HCAR2MAPTATMNPSR1ALDH1A1 | |
| SCHEMBL28631104 | 0.77 | ATM (0.37) | HCAR2ATM | |
| SCHEMBL9718851 | 0.77 | ATM (0.33) | HCAR2ATM | |
| SCHEMBL6894763 | 0.77 | HCAR2 (0.59) | HCAR2MAPTATMNPSR1CA12 | |
| SCHEMBL9709153 | 0.77 | HCAR2 (0.59) | HCAR2MAPTATMNPSR1CA12 | |
| Diethyl Maleate SCHEMBL42602 | 0.77 | HCAR2 (0.80) | HCAR2MAPTATMNPSR1CA12 | |
| Diethyl Maleate SCHEMBL60423 | 0.77 | HCAR2 (0.80) | HCAR2MAPTATMNPSR1CA12 | |
| Diethyl Maleate SCHEMBL43033 | 0.77 | HCAR2 (0.80) | HCAR2MAPTATMNPSR1CA12 | |
| Diethyl Maleate SCHEMBL2015895 | 0.77 | HCAR2 (0.80) | HCAR2MAPTATMNPSR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560550-B2 | Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives | RFS PHARMA, LLC (US) | 2009-07-14 | — | — | US | claimed |
| EP-1814939-A4 | ULTRAVIOLET LIGHT (UV) ABSORBING COMPOUNDS AND COMPOSITIONS CONTAINING UV ABSORBING COMPOUNDS | MILLIKEN & CO (US) | 2009-07-29 | — | — | EP | disclosed |
| US-7560550-B2 | Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives | RFS PHARMA, LLC (US) | 2009-07-14 | — | — | US | disclosed |
| US-7381762-B2 | Ultraviolet light (UV) absorbing compounds and compositions containing UV absorbing compounds | MILLIKEN & COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| EP-1648894-B1 | METHOD FOR THE PRODUCTION OF OH PROTECTED [4-(2.6-DIAMINO-9H-PURINE-9-YL)- 1.3-DIOXOLANE-2-YL]METHANOL DERIVATIVES | WACKER CHEMIE AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1814939-A2 | ULTRAVIOLET LIGHT (UV) ABSORBING COMPOUNDS AND COMPOSITIONS CONTAINING UV ABSORBING COMPOUNDS | Milliken&Company (US) | 2007-08-08 | — | — | EP | disclosed |
| US-20060211855-A1 | Method for the production of oh protected{4-(2.6-diamino-9h-purine-9-yl)-1.3-dioxolane-2-yl] methanol derivatives | WACKER CHEMIE AG (DE) | 2006-09-21 | — | — | US | disclosed |
| CN-1816532-A | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents | SCHERING AG (DE) | 2006-08-09 | — | — | CN | disclosed |
| EP-1648894-A1 | METHOD FOR THE PRODUCTION OF OH PROTECTED [4-(2.6-DIAMINO-9H-PURINE-9-YL)- 1.3-DIOXOLANE-2-YL]METHANOL DERIVATIVES | Wacker Chemie AG (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2006023687-A2 | ULTRAVIOLET LIGHT (UV) ABSORBING COMPOUNDS AND COMPOSITIONS CONTAINING UV ABSORBING COMPOUNDS | MILLIKEN & COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060041038-A1 | Ultraviolet light (UV) absorbing compounds and compositions containing UV absorbing compounds | MILLIKEN & COMPANY | 2006-02-23 | — | — | US | disclosed |
| WO-2005012302-A1 | METHOD FOR THE PRODUCTION OF OH PROTECTED [4-(2.6-DIAMINO-9H-PURINE-9-YL)- 1.3-DIOXOLANE-2-YL]METHANOL DERIVATIVES | WACKER CHEMIE AG (DE) | 2005-02-10 | — | — | WO | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211855-A1 | Method for the production of oh protected{4-(2.6-diamino-9h-purine-9-yl)-1.3-dioxolane-2-yl] methanol derivatives | FUT6, FUT5, ST6GAL1 | HCAR2 793/4885MAPT 4596/4885ATM 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.