⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351164 | 0.81 | USP2 (0.41) | — | |
| SCHEMBL350018 | 0.80 | OPRM1 (0.38) | — | |
| SCHEMBL351227 | 0.74 | MEN1 (0.46) | — | |
| SCHEMBL4228827 | 0.73 | CNR2 (0.38) | — | |
| SCHEMBL22468376 | 0.72 | CNR2 (0.30) | — | |
| SCHEMBL1936290 | 0.66 | FFAR3 (0.33) | — | |
| SCHEMBL23345220 | 0.66 | CYP4F2 (0.42) | — | |
| SCHEMBL17763731 | 0.66 | TET3 (0.30) | — | |
| SCHEMBL20240585 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL3952636 | 0.65 | SPR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |