SCHEMBL396749

SCHEMBL396749

CC(C)(C)c1cc(Br)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.61
▸ ALOX15 P16050 7/20 0.61
▸ CYP2C9 P11712 2/20 0.61
▸ HSD17B10 Q99714 2/20 0.61
▸ LMNA P02545 2/20 0.61
▸ NR1I2 O75469 1/20 0.61
▸ MIF P14174 1/20 0.61
▸ TYR P14679 1/20 0.61
▸ HTT P42858 1/20 0.61
▸ NFE2L2 Q16236 1/20 0.61
▸ CYP1A2 P05177 2/20 0.54
▸ KDM4E B2RXH2 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ ATP2A2 P16615 1/20 0.54
▸ ATP2A3 Q93084 1/20 0.54
▸ TDP1 Q9NUW8 3/20 0.48
▸ TSHR P16473 2/20 0.48
▸ PTGDR2 Q9Y5Y4 1/20 0.46
▸ CA2 P00918 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510666 0.90 ALDH1A1 (0.67) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL1764594 0.85 ALDH1A1 (0.45) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL15956741 0.84 ALOX15 (0.48) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL2788496 0.84 ALDH1A1 (0.53) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL30390153 0.82 ALOX15 (0.54) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL6044777 0.82 ALOX15 (0.54) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL6452950 0.79 ALOX15 (0.43) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL30874683 0.78 PTGDR2 (0.46) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL9248443 0.78 PTGDR2 (0.46) ALDH1A1ALOX15CYP2C9HSD17B10LMNA
SCHEMBL6153419 0.78 ALOX15 (0.42) ALDH1A1ALOX15CYP2C9HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 — — CN claimed
CN-114195624-B Preparation method of butyl hydroxyanisole 广东东阳光药业股份有限公司 2025-02-11 — — CN claimed
CN-119350639-A Micron-scale stable trimetallic MOF oxygen evolution catalyst and preparation method and application thereof 浙江工业大学 2025-01-24 — — CN claimed
CN-114195624-A Preparation method of butyl hydroxy anisole 广东东阳光药业有限公司 2022-03-18 — — CN claimed
CN-113966739-A Dinotefuran granules and production process thereof 广西乐土生物科技有限公司 2022-01-25 — — CN claimed
CN-113956098-A Method for preventing and treating sugarcane borers 广西乐土生物科技有限公司 2022-01-21 — — CN claimed
CN-113698246-A Method for preventing and treating sugarcane borers 广西乐土生物科技有限公司 2021-11-26 — — CN claimed
CN-1745198-A Method of preparing brominated hydroxy aromatic compounds GEN ELECTRIC (US) 2006-03-08 — — CN claimed
US-6827836-B2 With high para selectivity; hydrogen bromide not generated as a by-product; GENERAL ELECTRIC COMPANY 2004-12-07 — — US claimed
WO-2004050954-A1 METHOD OF PREPARING BROMINATED HYDROXY AROMATIC COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2004-06-17 — — WO claimed
US-20040104126-A1 Method of preparing brominated hydroxy aromatic compounds GENERAL ELECTRIC COMPANY 2004-06-03 — — US claimed
US-4898993-A Process for preparing 2-tert-butyl-4-methoxyphenol BROMINE COMPOUNDS LIMITED (IL) 1990-02-06 — — US claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 — — CN disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 — — US disclosed
US-20260078136-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR PROTEOSTASIS THERAPEUTICS INC (US) 2026-03-19 — — US disclosed
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. 2025-05-22 — — US disclosed
EP-0679628-A1 Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) 1995-11-02 — — EP disclosed
EP-0661258-A1 Biaromatic propynyl compounds, pharmaceutical compositions and cosmetics containing them and their uses CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) 1995-07-05 — — EP disclosed
US-4898993-A Process for preparing 2-tert-butyl-4-methoxyphenol BROMINE COMPOUNDS LIMITED (IL) 1990-02-06 — — US disclosed
US-4898993-A Process for preparing 2-tert-butyl-4-methoxyphenol BROMINE COMPOUNDS LIMITED (IL) 1990-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163038-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC ALDH1A1 4185/4885ALOX15 3000/4885CYP2C9 4713/4885
US-20260078136-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR CFTR, SCNN1B, SCNN1A ALDH1A1 2383/4885ALOX15 4473/4885CYP2C9 1034/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 ALDH1A1 100/4885ALOX15 922/4885CYP2C9 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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