Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP13 | P45452 | 6/20 | 0.44 |
| ▸ | MMP3 | P08254 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 5/20 | 0.44 |
| ▸ | MMP14 | P50281 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464542 | 0.79 | CNR2 (0.62) | CNR2CNR1MAPT | |
| SCHEMBL3967653 | 0.76 | MMP13 (0.40) | CNR2CNR1MMP2MMP13MMP3 | |
| SCHEMBL1463607 | 0.74 | ATM (0.55) | MMP13MMP9MMP1MAPT | |
| SCHEMBL1464356 | 0.74 | MMP2 (0.65) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3968259 | 0.72 | CNR2 (0.51) | CNR2CNR1MAPT | |
| SCHEMBL1464683 | 0.71 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL3964901 | 0.71 | CNR2 (0.52) | CNR2CNR1MAPT | |
| SCHEMBL3967702 | 0.70 | MMP13 (0.51) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3964990 | 0.69 | MMP2 (0.48) | CNR2CNR1MMP2MMP13MMP3 | |
| SCHEMBL3968969 | 0.69 | ATM (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |