Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.40 |
| ▸ | MMP2 | P08253 | 10/20 | 0.40 |
| ▸ | MMP9 | P14780 | 10/20 | 0.40 |
| ▸ | MMP3 | P08254 | 7/20 | 0.40 |
| ▸ | MMP8 | P22894 | 7/20 | 0.40 |
| ▸ | MMP14 | P50281 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967650 | 0.76 | CNR2 (0.50) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL1464356 | 0.65 | MMP2 (0.65) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL1463607 | 0.64 | ATM (0.55) | MMP13MMP9MMP1CYP3A4CYP2C19 | |
| SCHEMBL1464751 | 0.64 | MMP2 (0.57) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL1464315 | 0.63 | MMP13 (0.59) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL1464643 | 0.63 | MMP2 (0.57) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL1464255 | 0.63 | CNR2 (0.60) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL3967702 | 0.62 | MMP13 (0.51) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL3964990 | 0.62 | MMP2 (0.48) | MMP13MMP2MMP9MMP3MMP8 | |
| SCHEMBL3968969 | 0.61 | ATM (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |